- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Hedrick, P. W.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Hedrick, P. W.
Genetics, Vol 132, 575-581, Copyright © 1992
INVESTIGATIONS |
Female Choice and Variation in the Major Histocompatibility Complex
P. W. Hedrick
Department of Zoology, Arizona State University, Tempe, Arizona 85287
The cause of the high genetic variability in the major histocompatibility complex (MHC) is not entirely clear. Recently, two reports suggest that female mice prefer to mate with males different from them at the MHC. A model of female choice appropriate for those observations is developed here. Female choice can in fact reduce the observed proportions of homozygotes, maintain genetic polymorphism, influence mating-type frequencies and generate gametic disequilibrium.
This article has been cited by other articles:
 |
|
 |
|
  D. J. Penn, K. Damjanovich, and W. K. Potts MHC heterozygosity confers a selective advantage against multiple-strain infections PNAS, August 20, 2002; 99(17): 11260 - 11264. [Abstract] [Full Text] [PDF]
|
|