Genetics, Vol 118, 319-327, Copyright © 1988


INVESTIGATIONS

The Hox-2 Homeo Box Gene Complex on Mouse Chromosome 11 Is Closely Linked to Re

C. P. Hart, D. K. Dalton, L. Nichols, L. Hunihan, T. H. Roderick, S. H. Langley, B. A. Taylor and F. H. Ruddle
Department of Biology, Yale University, New Haven, Connecticut 06511

Restriction fragment length polymorphisms have been identified between inbred strains of mice for the homeo box gene complex Hox-2. These genetic markers were used to follow the segregation of different Hox-2 alleles among recombinant inbred strains of mice and among the progeny of a three point genetic cross. The results place the Hoax-2 locus approximately 1 cM from the rex (Re) locus on mouse chromosome 11.