- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Simmons, M. J.
- Articles by Zunt, J. R.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Simmons, M. J.
- Articles by Zunt, J. R.
The Influence of Nonautonomous P Elements on Hybrid Dysgenesis in Drosophila melanogaster
Michael J. Simmons 1, John D. Raymond 1, Michael J. Boedigheimer 1, and Joseph R. Zunt 1
1 Department of Genetics and Cell Biology, University of Minnesota,
St. Paul, Minnesota 55108-1095
An inbred line of the M' strain Muller-5 Birmingham was studied for its abilities to affect P-M hybrid dysgenesis. This strain possesses 57 P elements, all of which are apparently defective in the production of the P transposase. In combination with transposase-producing elements, these nonautonomous elements can enhance or diminish the incidence of hybrid dysgenesis, depending on the trait that is studied. Dysgenic flies that have one or more paternally-derived chromosomes with these elements partially repress the instability of the P element insertion mutation, sn w; however, such flies have elevated frequencies of another dysgenic trait, GD sterility, and also show distorted segregation ratios. An explanation is presented in which all of these phenomena are unified as manifestations of the kinetics of P element activation in the germ line. The progeny of Muller-5 Birmingham females exhibit partial repression of both sn w instability and GD sterility. This repression appears to involve a factor that can be transmitted maternally through at least two generations. This mode of repression therefore conforms to the pattern of inheritance of the P cytotype, the condition that brings about nearly total repression of P element activity in some strains. Models in which this repression could arise from the nonautonomous P elements of Muller-5 Birmingham are discussed.
Submitted on May 4, 1987Accepted on August 19, 1987
This article has been cited by other articles:
 |
|
 |
|
  M. J. Simmons, J. B. Niemi, D.-F. Ryzek, C. Lamour, J. W. Goodman, W. Kraszkiewicz, and R. Wolff Cytotype Regulation by Telomeric P Elements in Drosophila melanogaster: Interactions With P Elements From M' Strains Genetics, August 1, 2007; 176(4): 1957 - 1966. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. G. JONES, F. M. CARLAND, P. MALIGA, and H. K. DOONER Visual Detection of Transposition of the Maize Element Activator (Ac) in Tobacco Seedlings Science, April 14, 1989; 244(4901): 204 - 207. [Abstract] [PDF]
|
|