HIDDEN ELECTROPHORETIC VARIATION AT THE XANTHINE DEHYDROGENASE LOCUS IN A NATURAL POPULATION OF DROSOPHILA MELANOGASTER

Barbara Ann Buchanan ¹ and Diana L. E. Johnson ¹

¹ Department of Biological Sciences, The George Washington University, Washington, D.C. 20052

Sixty-two isochromosomal lines of D. melanogaster were screened for cryptic electrophoretic variation at the xanthine dehydrogenase (XDH) locus. Sequential polyacrylamide vertical slab gel electrophoresis was performed using four electrophoretic criteria. A total of 15 classes of electromorphs were revealed. D. melanogaster appears to exhibit as much polymorphism at this locus as other extensively studied Drosophila species.—No evidence for loci on the X or second chromosomes which modified XDH mobility was found. Six of the electromorphs were mapped to the Xdh ( ry) structural locus. Eight of the remaining nine classes exhibited mobility variation consistent with structural variation at the Xdh locus. The final class exhibited aberrant patterns and is under further study.

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